U=U undetectable = untrasmittable

The “Italian Consensus Conference on UequalsU was held on the 12th of November 2019 at the Ministero della Salute. The meeting was sponsored by SIMIT (Società di Malattie Infettive e Tropicali) e ICAR (Italian Conference on Aids and antiviral Research) and by the third sector associations involved in the fight agains HIV/AIDS to develop a conceptual consensus document on the validity of the concept that a HIV positive person on therapy for at least six months and with a viral load below the detection limit cannot transmit infection to his/her partner.

Evidence of lack of infectivity potential with sexual intercourse is the result of a large core of research that define zero the risk of sexual transmission of HIV, in the absence of condom use, if the HIV partner is on an effective therapy with suppressed viremia.

Similarly the absence of HIV infections as a consequence of professional accidents between HIV negative carigivers/patients and HIV positive but efficiently treated and virologically suppressed HIV positive caregivers/patients offers evidence that even outside the sexual contest a HIV positive person on therapy for at least six months and with an undetectable viremia (< 200 copies/ml) does not undergo specific precautions or limitations of his/her working activity.